2024 – Full Member, Academy of Political and Legal Sciences of Ukraine 

2021 – Honorary Professor, Tashkent Pharmaceutical Institute

2012 – Full Member, European Academy of Sciences and Arts

2006    Honorary Academician, Ukrainian Medical Stomatological Academy

1994 – Full Member, Latvian Academy of Sciences
1994 – Full Professor, Latvian Institute of Organic Synthesis
1988 – Doctor habilitatus in Chemistry, State University of Leningrad (St.Petersburg), Faculty of Chemistry, Department of Organic Chemistry
1979 – 1980 Postdoctoral studies, University of Munich (Germany), Institute of Organic Chemistry, research leader Prof. R.Huisgen
1977 – Doctor of Sciences in Chemistry, Latvian Academy of Sciences, Institute of Organic Synthesis
1969 – Master of Sciences, Latvian State University, Faculty of Chemistry, Department of Organic Chemistry, speciality chemist

2024 – JSC Grindeks award for lifelong contribution to development of Mildronate

2016 – Latvian Academy of Sciences and JSC Grindeks Golden Owl Award for the development of novel cardioprotective medicines and evaluation of the mechanism of action

2015 – Medal “100th Anniversary of Prof. A.N.Kost”, awarded for outstanding achievements in heterocyclic chemistry

2015 – The Walter Zapp Medal for outstanding inventions in medicinal chemistry and rise of Latvian

prestige in the world

2014 – Certificate of Recognition of Cabinet of Ministers (Latvia)

2014 – Cicero’s Award for “Outstanding contribution to the development of world class medicines”

2010 – Latvian Academy of Sciences and Riga City Award

2009 – Grand Medal of the Latvian Academy of Sciences for creation of new competitive medicinal preparation and strengthening of innovative orientation in the Latvian Institute of Organic Synthesis

2006 – The Order of the Three Stars (4^th Class), Latvia, awarded for meritorious service on behalf of the Fatherland

2005 – WIPO Award Certificate and Golden Medal for long-term and highly productive work as inventor

2004 – St.George Medal (awarded by International rating Academy “Golden Fortune”)

2002 – The Gustavs Vanags Prize of Latvian Academy of Sciences for a cycle of papers “Synthesis and Trials of Bioactive Low-molecular NO-inductors and Donors”

1997 – The Solomon Hiller Medal for contribution to the development of medicinal preparations

1996 – The David Hieronymus Grindel Medal for merits in the synthesis and trials of drugs

1988 – Latvian State Prize in Science and Technology

2022 – New approaches to the development of personalized anticancer drugs. LAS full member Ivars Kalviņš, Dr.chem. Viktors Andrianovs, Dr.chem. Ilona Domračeva, Dr.chem. Iveta Kaņepe, Mg.sc.ing. Diana Zeļencova–Gopejenko, Mg.sc. Irēna Leite. Latvian Institute of Organic Synthesis.  

2021 - Integration of reliable technologies for protection against Covid-19 in healthcare and high-risk areas. LAS Full member Tālis Juhna, Dr.sc.ing. Linda Mežule, LAS Full member Ivars Kalviņš, LAS Full member Juris Purāns, LAS Full member Andris Šutka, Dr.sc.ing. Inga Dāboliņa, Dr.sc.ing. Inese Fiļipova, Dr.biol. Ilze Irbe, Dr.med. Ivars Vanadziņš, LAS Corresponding member Atis Elsts, Mg.iur. Andreta Slavinska, Dr.biol. Anna Zajakina, Dr.sc.ing. Andris Martinovs, Dr.phys. Atis Skudra, LAS Corresponding member Gita Rēvalde, Dr.sc.ing. Agris Ņikitenko, Dr.chem. Kārlis Pajuste, Mg.sc.ing. Aleksandrs Ļevinskis. Rīga Technical University, Latvian Institute of Organic Synthesis, Institute of Solid State Physics, University of Latvia, Latvian Biomedical Research and Study Centre, Rīga Stradiņš University, Institute of Atomic Physics and Spectroscopy, University of Latvia, Rēzekne Academy of Technologies, Latvian State Institute of Wood Chemistry, Institute of Electronics and Computer Science

2014 – An active anti-cancer drug Belinostat containing a compound developed by scientists of the Latvian Institute of Organic Synthesis has received US Food and Drug Administration (FDA) approval for clinical medical use for treatment of peripheral T-cell lymphoma. LAS academician Ivars Kalviņš, Dr.chem. Einārs Loža, Dr.chem. Klāra Dikovska, Latvian Institute of Organic Synthesis.

2013 – Accomplishment of chemical and experimental study of a new original cardioprotective drug candidate allowing to proceed with clinical trials of this substance. LAS academician Maija Dambrova, Dr.chem. Solveiga Grīnberga, LAS academician Ivars Kalviņš, Dr.pharm. Jānis Kūka, Dr.pharm. Edgars Liepiņš, Dr.chem. Daina Loļa, Dr.chem. Einārs Loža, LAS Corresponding Member Osvalds Pugovičs, Dr.pharm. Reinis Vilšķērsts, Latvian Institute of Organic Synthesis; Dr.med. Ilmārs Stonāns, JSC „Grindeks”.

2011 – Successful implementation of the first round of clinical trials of a new therapeutic substance applicable in the treatment of late complications of Parkinson’s disease. PhD Juris Fotins, Dr.chem. Aleksandrs Gutcaits, LAS academician Ivars Kalviņš, PhD Ronalds Zemribo, LAS Corresponding Member Valerjans Kauss, Latvian Institute of Organic Synthesis in cooperation with “Merz Pharmaceuticals”, Germany.

2007 – Mildronate has been demonstrated to have the ability to regulate mitochondrial processes that opens new possibilities in the treatment of neurodegenerative disorders. LAS academician Vija Kluša, LAS academician Ivars Kalviņš, Faculty of Medicine, University of Latvia, Latvian Institute of Organic Synthesis.

- R&D of novel physiologically active substances for the treatment of CNS, cardiovascular and malignant diseases, organic chemistry of heterocyclic compounds and amino acid analogues, investigation of biochemical mechanisms of action of new medicines, immunochemistry.

- I.Kalviņš with his team is an originator of the approved anti-ischemic drug Mildronate (meldonium), antitumor immunomodulator Leakadine, as well as novel meldonium containing pharmaceutical combinations (Kapicor, Mildronate GX,). Together with colleagues I. Kalviņš is discoverer of active pharmaceutical ingredient of FDA approved antitumor medicine belinostat as well as of meldonium-like cardioprotective drug under development.

- More than 450 scientific articles published (175 Scopus), 5 books, and more than 200 international conference proceedings.

- I.Kalviņš with his team is the originator of more than 250 inventions (protected by over 1350 patents, patent applications and author's testimonies).

 

- Head of the Project, Latvian State Research Program, 2020

- Head of the Project “Isoform selective PDI inhibitor: design, synthesis and SAR” (2018– 2020)

- Co-Head of the Project “Development of novel medicines for treatment and prophylaxes of diseases, diagnostic methods and kits, biomedical technologies for improvement of public health” of Latvian State Research Program “Public Health” (2010– 2013)

- Head of the Project “Molecular mechanisms, pharmacogenetics and novel medicines for complications treatment of diabetes and cardiovascular diseases” of Latvian State Research Program “Biomedicine for Public Health” (2014–2017)

- Co-head of Latvian State Research Program “Biomedicine for Public Health” (2014–- 2017)

- Coordinator of EU RegPot project InnovaBalt: “Strengthening the research and innovative capacities of the Latvian Institute of Organic Synthesis” (2013–2016)

- Head of the Project “Aziridin-2-carbonic acid derivatives as pH sensitive hybrid anticancer drugs”, Latvian Institute of Organic Synthesis (2016).

Since 2020 – present    President of the Latvian Academy of Sciences

Since 2014 – present    Head of Laboratory of Carbofunctional Compounds, senior researcher, Latvian Institute of Organic Synthesis

2015–2018 Chairman of Scientific Council, Latvian Institute of Organic Synthesis

2003–2015 Director, Latvian Institute of Organic Synthesis

1992–2014 Head of Department of Medicinal Chemistry, Latvian Institute of Organic Synthesis

1987–2003 Vice Director, Latvian Institute of Organic Synthesis

1986–2014 Head of Laboratory, Latvian Institute of Organic Synthesis

1981           Head of the Team, Institute of Organic Synthesis

1979           Principal Scientist, Institute of Organic Synthesis

1975           Junior Scientist, Institute of Organic Synthesis.

1996–1997, and 2001–2020  Professor, Riga Technical University

1997, and since 2001 – lecture course “Medicinal chemistry” and “Technology of API” for MSc and PhD students Riga Technical University and Riga Stradiņš University. Supervisor of 6 PhD student qualification works.

 

University of Latvia Council (Chair, April 11, 2022 - April 11, 2024)

University of Latvia Council (Member, 2022)

Latvian Academy of Sciences (Full Member, since 1994, Senator, since 2004)

Scientific Council of Latvia (Member, 1994–2001, 2010–2016, expert – since 2006)

Research and Innovation Strategy Council of Latvia (Member, since 2014)

Latvian Ministry of Economics, (Council “Pharmacy and Biomedicine”, Chairman, since 2016)

Latvian State Drug Agency (Steering Committee, Member, 1994–2002)

Liepāja University (Chairman of the Advisory Board, since 2013)

Riga Stradiņš University (Council for Promotion in Pharmacy, Chairman, since 2006, Member of the Advisory Board, since 2012)

Riga Technical University (Member of the Advisory Board, since 2013, Member of the Advisory Board of Faculty of Materials Science and Applied Chemistry, since 2007)

Latvian Union of Scientists (Chairman of the Council, since 2007)

Latvian Chemical Society (President, 1994–2000)

Association of Latvian Innovators (Chairman of the Board, since 2009)

Association of Latvian State Scientific Institutes (Chairman of the Board, 2009–2015)

Baltic Institute of Research, Technology and Innovation, BIRTI (Chairman of the Council 2012–2013, Member of the Council, since 2013)

Open public foundation “Taiho Latvian Fund” (Chairman of the Board, since 2011)

Journal “Chemistry of Heterocyclic Compounds” (Editor-in-Chief, 2010–2019)

Journal of Synthetic Organic Chemistry and Natural Products “Molecules” (Regional Editor, since 2006)

World Applied Sciences Journal (Member of the Editorial Board, since 2006)

Latvian Journal of Chemistry (Member of the Editorial Board, since 1996)

Journal “Proceedings of the Estonian Academy of Sciences” (Member of the Editorial Board, since 2006)

 

 

Photo by Jānis Brencis

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